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Study details
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A 2-part Phase 1b Clinical Trial to Evaluate CRB-913 in People with Obesity

Corbus Pharmaceuticals Inc.
NCT IDNCT07310901ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

252

Study length

about 8 months

Ages

18–75

Locations

15 sites in AL, AZ, CA +7

What this study is about

This trial is testing the safety of a new drug called CRB-913. It has two parts: Part 1 measures how the drug affects people's bodies, and Part 2 compares CRB-913 to a placebo (inactive pill) over 12 weeks to see if it helps with weight loss and blood levels of the drug.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take CRB-913
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Part 1: To evaluate the PK of a single dose of CRB-913 - Cmax, Part 1: To evaluate the PK of a single dose of CRB-913 - T1/2, Part 1: To evaluate the PK of a single dose of CRB-913 - Tmax, Part 2: To evaluate the safety of CRB-913 - TEAE

Secondary: Part 1: To evaluate the safety of a single dose of CRB-913 - TEAE, Part 2: To evaluate the PK of CRB-913 - Cmax, Part 2: To evaluate the PK of CRB-913 - Tmax