Study details
Enrolling now
Oral Steroid Taper After Total Knee Arthroplasty
Columbia University
NCT IDNCT07070882ClinicalTrials.gov data as of Apr 2026
Phase
Phase 1
Target enrollment
130
Study length
about 2 years
Ages
18+
Locations
1 site in NY
What this study is about
This trial is testing if an oral methylprednisolone taper helps reduce pain, opioid use, and nausea after knee replacement surgery. The goal is to see if adding this treatment to standard care improves outcomes for people undergoing total knee arthroplasty (TKA) for osteoarthritis.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Methylprednisolone
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Injection / IV
How treatment is administered
Treatment Assignment
Randomized & Blinded
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug classes
methylprednisolone
Drug routes
injection (Injection)
Body systems
Musculoskeletal