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Study details
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A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

Spyre Therapeutics, Inc.
NCT IDNCT07012395ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

645

Study length

about 2.8 years

Ages

18+

Locations

21 sites in CA, CO, FL +10

What this study is about

Researchers are testing a new treatment, SPY001, SPY002, or SPY003, alone or in combination with a placebo, for people with moderate to severe ulcerative colitis. The trial will last 1039 days and involve approximately 645 participants.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Placebo
  • 2.Take SPY001
  • 3.Take SPY002
  • +1 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Body systems

Gastroenterology