Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study
Phase 4
1,335
about 4.4 years
18–70
23 sites in AZ, CA, CO +15
What this study is about
This trial is testing the effectiveness of three migraine preventive medications: atogepant, propranolol, and topiramate. Participants will be randomly assigned to take one of these medications for 1606 days while tracking their headaches with a daily diary.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Atogepant 60 mg
- 2.Take Propranolol 160 mg
- 3.Take Topiramate 100 mg
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You are randomly assigned, but you will know your treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
atogepant, propranolol (Non-selective beta blocker; slows heart rate), topiramate
oral (Oral Tablet)
Secondary: Medication-Related Adverse Events, Migraine Specific Quality-of-Life - Role Function-Restrictive
Neurology