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Study details
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Depemokimab Trial for COPD

GlaxoSmithKline
NCT IDNCT06961214ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

960

Study length

about 4.2 years

Ages

40–80

Locations

54 sites in AL, CO, FL +16

What this study is about

This trial is testing depemokimab, a new medication, as an add-on treatment for adults with moderate to severe COPD and type 2 inflammation. The goal is to see if depemokimab helps improve symptoms in people who don't respond well to standard treatments.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Depemokimab
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

monoclonal antibody

Endpoints

Secondary: Annualized Rate of Exacerbations Requiring Emergency Department (ED) Visit or Hospitalization, Change from Baseline in Evaluating Respiratory Symptoms in Chronic Obstructive Pulmonary Disease (E-RS: COPD) Total Score at Week 52, Change from Baseline in St. George's Respiratory Questionnaire (SGRQ) Total Score at Week 52

Body systems

Respiratory