Skip to content
Study details
Enrolling now

A Study of a Novel Precision Medicine Approach for Obesity

Mayo Clinic
NCT IDNCT06814938ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

135

Study length

about 3.8 years

Ages

18–65

Locations

2 sites in FL, MN

What this study is about

Researchers are testing whether a saliva biomarker can predict how well semaglutide works to treat obesity. The trial will last 1378 days and involve approximately 135 participants. Participants will be assigned to receive either a placebo or semaglutide.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Placebo
  • 2.Take Semaglutide

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

semaglutide (GLP-1 agonist; stimulates insulin release)

Drug routes

oral (Oral Tablet)

Endpoints

Primary: Change in Total Body Weight at 24 weeks

Secondary: Change in Total Body Weight at 3 months, Change in Total Body Weight at 6 months, Change in Waist Circumference

Body systems

Endocrinology