Suvorexant Trial for AUD and PTSD
Phase 2
76
about 12 months
21–65
2 sites in CA, TX
What this study is about
This trial is testing if suvorexant (SUV) can reduce insomnia in adults with post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD). Participants will receive either a placebo or SUV, followed by a two-week abstinence period from alcohol. They will track their symptoms using daily diaries and attend clinic visits to assess outcomes.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Placebo
- 2.Take Suvorexant
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
suvorexant
oral (Oral Tablet)
Primary: Change in Insomnia Severity Index (ISI) score from baseline to Day 14.
Secondary: Change in PTSD total symptom severity score as measured by the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) from baseline to Day 14.
Psychiatry / Mental Health