Systemic Oral Glucocorticoids for Acute Osteoarthritis Pain
Phase 4
192
about 2.8 years
18+
1 site in PA
What this study is about
This trial is testing whether adding oral glucocorticoid medications to standard pain medication helps with osteoarthritis pain in the emergency department. It compares three groups: one receiving a placebo, one receiving prednisone, and one receiving dexamethasone, all along with ibuprofen. Participants will report their pain levels and any side effects during follow-up calls.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Dexamethasone
- 2.Take Placebo
- 3.Take Prednisone
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
dexamethasone, prednisone
injection, ocular, oral
Primary: Adverse Events (Safety Outcome), Change in Resting Pain Score at 3 Days (Effectiveness Outcome)
Secondary: Change in Ambulatory/Active Movement Pain Score at 1 Day, Change in Ambulatory/Active Movement Pain Score at 14 Days, Change in Ambulatory/Active Movement Pain Score at 3 Days, Change in Ambulatory/Active Movement Pain Score at 7 Days, Change in Resting Pain Score at 1 Day, Change in Resting Pain Score at 14 Days, Change in Resting Pain Score at 7 Days, Use of Rescue Medication for Pain (Acetaminophen)
Musculoskeletal