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Study details
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Pramipexole to Enhance Social Connections

University of California, San Diego
NCT IDNCT06269146ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

108

Study length

about 1.9 years

Ages

18–50

Locations

2 sites in CA, NY

What this study is about

This trial is testing if pramipexole, a medication, can improve social connectedness in adults experiencing anxiety or depression. Participants will take either a placebo pill or pramipexole for 687 days. It aims to understand how pramipexole affects brain function and behavior related to social reward processing.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Placebo Pill
  • 2.Take Pramipexole Pill

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

NERVOUS SYSTEM

Drug routes

oral

Body systems

Psychiatry / Mental Health