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Study details
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Placebo Impacts Sleep and Pain Modulation in Chronic Pain

University of Maryland, Baltimore
NCT IDNCT06225817ClinicalTrials.gov data as of Apr 2026
Target enrollment

111

Study length

about 2.3 years

Ages

18–88

Locations

1 site in MD

What this study is about

This trial is testing whether taking open-label placebo pills, along with an expectation management session, improves chronic pain, sleep quality, and mood in people with temporomandibular disorders (TMD). Participants will be randomly assigned to take either open-label placebo pills alone, open-label placebo pills plus the expectation management session, or standard care. Researchers will compare these groups on measures of pain intensity, interference, anxiety, depression, and sleep quality.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Open-label placebo pills

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Chronic pain intensity, Sleep efficiency