A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Phase 4
65
about 3.1 years
18–65
40 sites in AL, AZ, CA +19
What this study is about
Researchers are testing whether a treatment with vedolizumab and tofacitinib is effective for adults with ulcerative colitis. The trial also explores the effect of vedolizumab alone after this combined treatment.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Tofacitinib
- 2.Take Vedolizumab
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
tofacitinib, vedolizumab
oral (Oral Tablet), injection, intravenous
Secondary: Change in C-Reactive Protein Levels (CRP) From Baseline, Change in Functional Assessment of Chronic Illness Therapy Fatigue (FACIT-F) Score From Baseline, Number of Participants With Adverse Events (AEs), Adverse Events of Special Interest (AESIs) and Serious Adverse Events (SAEs)
Gastroenterology