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Study details
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MDMA-assisted Therapy for Fibromyalgia

Spaulding Rehabilitation Hospital
NCT IDNCT06066853ClinicalTrials.gov data as of Apr 2026
Phase

EARLY_PHASE1

Target enrollment

20

Study length

about 12 months

Ages

21–65

Locations

1 site in MA

What this study is about

Researchers are testing if MDMA-assisted therapy can help people with fibromyalgia. The trial will involve two sessions of MDMA combined with neuroimaging and integrative therapy, along with baseline and follow-up imaging. The goal is to see how this treatment affects the patient-clinician relationship and brain activity in these patients.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take MDMA

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug routes

oral

Endpoints

Primary: Change in self-reported pain severity and pain interference (Brief Pain Inventory)

Body systems

Musculoskeletal