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Study details
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A Study to Investigate the Safety, Tolerability, and Efficacy of BxC-I17e Single and Multiple Dose SC Injection in Patients With Moderate to Severe Atopic Dermatitis

Brexogen Inc.
NCT IDNCT06055361ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

45

Study length

about 3 years

Ages

18+

Locations

3 sites in AR, PA

What this study is about

This trial is testing a new treatment called BxC-I17e for people with moderate to severe atopic dermatitis. The goal is to see if it's safe, well-tolerated, and helps improve the condition.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take BxC-I17e (primed iMSC derived Extracellular vesicles(EV))
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Incidence of treatment-emergent adverse events (TEAEs)

Secondary: Change and percent change in Pruritus Numerical Rating Scale (NRS), Incidence, severity and relationship of adverse events(AEs), Number of abnormalities and change from baseline in Vital signs

Body systems

Dermatology