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Study details
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Amplification of Positivity for Alcohol Use

Laureate Institute for Brain Research, Inc.
NCT IDNCT06030154ClinicalTrials.gov data as of Apr 2026
Target enrollment

100

Study length

about 2.8 years

Ages

18–65

Locations

1 site in OK

What this study is about

Researchers are testing a new treatment called Amplification of Positivity Therapy to help people with alcohol use disorder, anxiety, and depression. Participants will be asked about their experiences with the therapy, which may lead to changes in the treatment itself. The trial will also compare this therapy to Cognitive Behavioral Therapy (CBT) for individuals experiencing these conditions.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Participate in Amplification of Positivity Therapy
  • 2.Participate in Cognitive Behavioral Therapy
  • 3.Participate in Surveys and Interviews

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Change in positive affect self-report measured with National Institute of Health (NIH) Patient Reported Outcome Measurement and Information System (PROMIS) Positive Affect score

Secondary: Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Anxiety Scale, Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Depression Scale, Change in the Patient-Reported Outcomes Measurement Information System (PROMIS) Meaning and Purpose Scale

Procedures

therapy

Body systems

Psychiatry / Mental Health