Study details
Enrolling now
The Osteoarthritis Prevention Study
Wake Forest University
NCT IDNCT05946044ClinicalTrials.gov data as of Apr 2026
Target enrollment
1,230
Study length
about 5.4 years
Ages
50+
Sex
Female only
Locations
3 sites in MA, NC
What this study is about
Researchers are testing if a diet and exercise program can help prevent osteoarthritis in women aged 50 or older who are obese. The trial will compare this approach to not doing anything (a control group) over several years.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Participate in Diet and Exercise
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Standard
How treatment is administered
Treatment Assignment
Randomized & Blinded
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Endpoints
Primary: Structural knee Osteoarthritis (OA) MRI change Scores
Secondary: Health-Related Quality of Life Scores, Knee Pain Scores
Body systems
Musculoskeletal