Study details
Enrolling now
Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
VA Office of Research and Development
NCT IDNCT05937854ClinicalTrials.gov data as of Apr 2026
Phase
Phase 2
Target enrollment
126
Study length
about 3.7 years
Ages
35–89
Locations
5 sites in CO, GA, MA +2
What this study is about
Researchers are testing whether tadalafil, a medication, improves shortness of breath in Veterans with Chronic Obstructive Pulmonary Disease (COPD) and high blood pressure in the lungs. The trial will also assess if tadalafil improves quality of life, exercise endurance, and other health measures.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Placebo
- 2.Take Tadalafil
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Oral
How treatment is administered
Treatment Assignment
Randomized & Blinded
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug classes
tadalafil
Drug routes
oral (Oral Tablet)
Endpoints
Secondary: physical activity
Body systems
Respiratory