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Study details
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Artificial Pancreas Technology to Reduce Glycemic Variability and Improve Cardiovascular Health in Type 1 Diabetes

University of Virginia
NCT IDNCT05653518ClinicalTrials.gov data as of Apr 2026
Target enrollment

40

Study length

about 2.2 years

Ages

18–40

Locations

1 site in VA

What this study is about

Researchers are testing whether artificial pancreas technology can improve blood sugar control, reduce blood glucose variability, and potentially benefit cardiovascular health in people with type 1 diabetes. The trial will evaluate if improvements in blood sugar levels lead to a decrease in inflammation and other markers of heart disease risk.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Use Sensor augmented pump (SAP) therapy
  • 2.Use Tandem t:slim X2 with Control-IQ Technology

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Brachial artery flow-mediated dilation (FMD), Carotid Femoral Pulse Wave Velocity (cfPWV), High-sensitivity C-reactive protein (hs-CRP), Insulin sensitivity, Interleukin-6 (IL-6), Myocardial Perfusion (measured by contrast-enhanced ultrasound [CEU])

Body systems

Endocrinology