Study details
Enrolling now
A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT IDNCT05412225ClinicalTrials.gov data as of Apr 2026
Phase
Phase 1
Target enrollment
60
Study length
about 4 years
Ages
18+
Sex
Female only
Locations
7 sites in NJ, NY
What this study is about
This trial is testing a new way to treat breast cancer that involves giving radiotherapy before surgery and performing immediate reconstruction at the same time. The goal is to see if this approach is safe and feasible compared to the standard treatment.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive Neoadjuvant radiotherapy
- 2.Undergo Pre-neoadjuvant radiotherapy (NART) biopsy
- 3.Undergo Unilateral total mastectomy with axillary lymph node dissection
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Standard
How treatment is administered
Treatment Assignment
All receive treatment
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Procedures
radiation, surgery
Body systems
Oncology