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Study details
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Nitrous Oxide as Treatment for Fibromyalgia

University of Chicago
NCT IDNCT05357066ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

50

Study length

about 5.1 years

Ages

18–75

Locations

1 site in IL

What this study is about

Researchers are testing whether nitrous oxide can help reduce pain in people with fibromyalgia, a chronic condition causing widespread musculoskeletal pain. The trial will compare the effects of nitrous oxide to a placebo (an inactive substance).

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Nitrous oxide gas for inhalation
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
inhaled

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

anesthetic (Inhaled anesthetic gas; causes analgesia and mild anesthesia)

Drug routes

inhaled

Endpoints

Secondary: Hospital Anxiety and Depression Scale

Body systems

Musculoskeletal