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Study details
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A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery

Memorial Sloan Kettering Cancer Center
NCT IDNCT05130801ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

55

Study length

about 5 years

Ages

18+

Sex

Female only

Locations

2 sites in NJ, NY

What this study is about

Researchers are testing whether pre-operative mpMRI with additional sequences can improve surgical outcomes by providing more accurate information about the extent and acidity of the tumor than standard MRI. The trial also tests if using the fluorescent imaging agent pHLIP ICG during surgery, along with NIRF imaging, allows surgeons to see cancer cells in the tumor and nearby tissues more clearly and remove them completely.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Undergo pHLIP® ICG NIRF imaging

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Dose-limiting toxicity (DLT)

Procedures

imaging

Devices

diagnostic

Body systems

Oncology