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Study details
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Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714

University of Alabama at Birmingham
NCT IDNCT03759522ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

120

Study length

about 7.2 years

Ages

18–65

Locations

1 site in AL

What this study is about

This trial is testing a treatment to measure neuroinflammation using a PET scan. The goal is to see if people with chronic pain and fatigue have higher levels of neuroinflammation than healthy individuals, as measured by the PET scan.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take DPA-714 PET/MRI

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Neuroinflammation will be measured in healthy volunteers and compared to neuroinflammation in individuals with pain and fatigue, as measured with [F-18]DPA-714-PET/MRI.

Body systems

Neurology, Musculoskeletal