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Study details
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Objectively Diagnose and Monitor Treatment of Light Sensitivity

Randy Kardon
NCT IDNCT03694626ClinicalTrials.gov data as of Apr 2026
Target enrollment

120

Study length

about 8.5 years

Ages

18–80

Locations

1 site in IA

What this study is about

This trial is testing a new way to diagnose and monitor treatment for light sensitivity, headaches, traumatic brain injury, by measuring facial features, pupil responses, retinal electrical responses, and autonomic nerve responses to light. It uses devices like wrist-watch sensors and OCT scans.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Use Electrophysiology
  • 2.Use Ocular Coherence Tomography (OCT)
  • 3.Use Pupillography
  • +2 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Correlation of objective biological marker of light sensitivity to macula (structure found in the back of the eye)., Correlation of objective biological marker of light sensitivity to optic nerve structures

Devices

monitoring

Body systems

Neurology