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Study details
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A Prospective, Randomized, Open Label Trial of Two Doses of Oral Betaine

Southern California Institute for Research and Education
NCT IDNCT03073343ClinicalTrials.gov data as of Apr 2026
Target enrollment

48

Study length

about 12 years

Ages

18–75

Locations

1 site in CA

What this study is about

This trial is testing two different doses of oral betaine to see if it helps with liver problems. Patients will take the betaine as a powder mixed in water and drink it daily for 4431 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Betaine (trimethyglycine)

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

betaine

Drug routes

oral (Oral Tablet)

Endpoints

Primary: Change in alanine aminotransferase (ALT) level in all study participants

Secondary: Compare changes in alanine aminotransferase (ALT) level in both cohorts

Body systems

Endocrinology