Study details
Enrolling now
MRS Measurement of Glutamate and GABA Metabolism in Brain
National Institute of Mental Health (NIMH)
NCT IDNCT00109174ClinicalTrials.gov data as of Apr 2026
Target enrollment
200
Study length
about 24 years
Ages
18–65
Locations
1 site in MD
What this study is about
This trial is testing a treatment using magnetic resonance spectroscopy (MRS) to measure the transfer of carbon as it's naturally metabolized from glucose into specific chemical transmitters. The goal is to measure the rate of production of important excitatory neurotransmitters (glutamate) and inhibitory neurotransmitters (GABA).
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Use 3T and 7T device
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Standard
How treatment is administered
Treatment Assignment
All receive treatment
Everyone gets the investigational treatment.